4,054 research outputs found

    The psychology of driving automation: A discussion with Professor Don Norman

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    Introducing automation into automobiles had inevitable consequences for the driver and driving. Systems that automate longitudinal and lateral vehicle control may reduce the workload of the driver. This raises questions of what the driver is able to do with this 'spare' attentional capacity. Research in our laboratory suggests that there is unlikely to be any spare capacity because the attentional resources are not 'fixed'. Rather, the resources are inextricably linked to task demand. This paper presents some of the arguments for considering the psychological aspects of the driver when designing automation into automobiles. The arguments are presented in a conversation format, based on discussions with Professor Don Norman. Extracts from relevant papers to support the arguments are presented

    In loco intellegentia: Human factors for the future European train driver

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    The European Rail Traffic Management System (ERTMS) represents a step change in technology for rail operations in Europe. It comprises track-to-train communications and intelligent on-board systems providing an unprecedented degree of support to the train driver. ERTMS is designed to improve safety, capacity and performance, as well as facilitating interoperability across the European rail network. In many ways, particularly from the human factors perspective, ERTMS has parallels with automation concepts in the aviation and automotive industries. Lessons learned from both these industries are that such a technology raises a number of human factors issues associated with train driving and operations. The interaction amongst intelligent agents throughout the system must be effectively coordinated to ensure that the strategic benefits of ERTMS are realised. This paper discusses the psychology behind some of these key issues, such as Mental Workload (MWL), interface design, user information requirements, transitions and migration and communications. Relevant experience in aviation and vehicle automation is drawn upon to give an overview of the human factors challenges facing the UK rail industry in implementing ERTMS technology. By anticipating and defining these challenges before the technology is implemented, it is hoped that a proactive and structured programme of research can be planned to meet them

    Measuring situation awareness in complex systems: Comparison of measures study

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    Situation Awareness (SA) is a distinct critical commodity for teams working in complex industrial systems and its measurement is a key provision in system, procedural and training design efforts. This article describes a study that was undertaken in order to compare three different SA measures (a freeze probe recall approach, a post trial subjective rating approach and a critical incident interview technique) when used to assess participant SA during a military planning task. The results indicate that only the freeze probe recall method produced a statistically significant correlation with performance on the planning task and also that there was no significant correlation between the three methods, which suggests that they were effectively measuring different things during the trials. In conclusion, the findings, whilst raising doubts over the validity of post trial subjective rating and interview-based approaches, offer validation evidence for the use of freeze probe recall approaches to measure SA. The findings are subsequently discussed with regard to their implications for the future measurement of SA in complex collaborative systems

    Representing situation awareness in collaborative systems: A case study in the energy distribution domain

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    The concept of Distributed Situation Awareness (DSA) is currently receiving increasing attention from the human factors community. This article investigates DSA in a collaborative real-world industrial setting by discussing the results derived from a recent naturalistic study undertaken within the UK energy distribution domain. The results describe the DSA-related information used by the networks of agents involved in the scenarios analysed, the sharing of this information between the agents, and the salience of different information elements used. Thus the structure, quality and content of each network’s DSA is discussed, along with the implications for DSA theory. The findings reinforce the notion that when viewing SA in collaborative systems, it is useful to focus on the co-ordinated behaviour of the system itself, rather than on the individual as the unit of analysis and suggest that the findings from such assessments can potentially be used to inform system, procedure and training design

    Синтез нечетких систем автоматического управления генетическими алгоритмами по векторным критериям в среде MATLAB

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    Задачи многокритериального параметрического синтеза систем управления сведены к задачам оптимизации векторных целевых функций, решение которых позволяет удержать процесс синтеза систем в допустимой области. Для оптимизации векторных целевых функций систем автоматического управления модифицированы бинарный и непрерывный генетические алгоритмы. Показана эффективность применения модифицированных генетических алгоритмов для синтеза систем управления путем оптимизации векторных целевых функций. Рассмотрение задач синтеза линейных и нечетких ПИД регуляторов показало, что в задаче синтеза нечеткого регулятора определяется вектор переменных параметров большей размерности, а в модели системы управления вместо линейных уравнений применяются нелинейные уравнения с использованием системы нечеткого вывода

    Global transcriptional response of pig brain and lung to natural infection by Pseudorabies virus

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    <p>Abstract</p> <p>Background</p> <p>Pseudorabies virus (PRV) is an alphaherpesviruses whose native host is pig. PRV infection mainly causes signs of central nervous system disorder in young pigs, and respiratory system diseases in the adult.</p> <p>Results</p> <p>In this report, we have analyzed native host (piglets) gene expression changes in response to acute pseudorabies virus infection of the brain and lung using a printed human oligonucleotide gene set from Illumina. A total of 210 and 1130 out of 23,000 transcript probes displayed differential expression respectively in the brain and lung in piglets after PRV infection (p-value < 0.01), with most genes displaying up-regulation. Biological process and pathways analysis showed that most of the up-regulated genes are involved in cell differentiation, neurodegenerative disorders, the nervous system and immune responses in the infected brain whereas apoptosis, cell cycle control, and the mTOR signaling pathway genes were prevalent in the infected lung. Additionally, a number of differentially expressed genes were found to map in or close to quantitative trait loci for resistance/susceptibility to pseudorabies virus in piglets.</p> <p>Conclusion</p> <p>This is the first comprehensive analysis of the global transcriptional response of the native host to acute alphaherpesvirus infection. The differentially regulated genes reported here are likely to be of interest for the further study and understanding of host viral gene interactions.</p

    Development of a generic activities model of command and control

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    This paper reports on five different models of command and control. Four different models are reviewed: a process model, a contextual control model, a decision ladder model and a functional model. Further to this, command and control activities are analysed in three distinct domains: armed forces, emergency services and civilian services. From this analysis, taxonomies of command and control activities are developed that give rise to an activities model of command and control. This model will be used to guide further research into technological support of command and control activities

    Systematic Global Analysis of Genes Encoding Protein Phosphatases in Aspergillus fumigatus.

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    Aspergillus fumigatus is a fungal pathogen that causes several invasive and noninvasive diseases named aspergillosis. This disease is generally regarded as multifactorial, considering that several pathogenicity determinants are present during the establishment of this illness. It is necessary to obtain an increased knowledge of how, and which, A. fumigatus signal transduction pathways are engaged in the regulation of these processes. Protein phosphatases are essential to several signal transduction pathways. We identified 32 phosphatase catalytic subunit-encoding genes in A. fumigatus, of which we were able to construct 24 viable deletion mutants. The role of nine phosphatase mutants in the HOG (high osmolarity glycerol response) pathway was evaluated by measuring phosphorylation of the p38 MAPK (SakA) and expression of osmo-dependent genes. We were also able to identify 11 phosphatases involved in iron assimilation, six that are related to gliotoxin resistance, and three implicated in gliotoxin production. These results present the creation of a fundamental resource for the study of signaling in A. fumigatus and its implications in the regulation of pathogenicity determinants and virulence in this important pathogen

    Opportunities for topical antimicrobial therapy: permeation of canine skin by fusidic acid

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    BACKGROUND: Staphylococcal infection of the canine epidermis and hair follicle is amongst the commonest reasons for antimicrobial prescribing in small animal veterinary practice. Topical therapy with fusidic acid (FA) is an attractive alternative to systemic therapy based on low minimum inhibitory concentrations (MICs, commonly <0.03 mg/l) documented in canine pathogenic staphylococci, including strains of MRSA and MRSP (methicillin-resistant Staphylococcus aureus and S. pseudintermedius). However, permeation of canine skin by FA has not been evaluated in detail. This study aimed to define the degree and extent of FA permeation in canine skin in vitro from two sites with different hair follicle density following application of a licensed ophthalmic formulation that shares the same vehicle as an FA-betamethasone combination product approved for dermal application in dogs. Topical FA application was modelled using skin held in Franz-type diffusion cells. Concentrations of FA in surface swabs, receptor fluid, and transverse skin sections of defined anatomical depth were determined using high-performance liquid chromatography and ultraviolet (HPLC-UV) analysis. RESULTS: The majority of FA was recovered by surface swabs after 24 h, as expected (mean ± SEM: 76.0 ± 17.0%). FA was detected within 424/470 (90%) groups of serial sections of transversely cryotomed skin containing follicular infundibula, but never in 48/48 (100%) groups of sections containing only deeper follicular structures, nor in receptor fluid, suggesting that FA does not permeate beyond the infundibulum. The FA concentration (mean ± SEM) in the most superficial 240 μm of skin was 2000 ± 815 μg/g. CONCLUSIONS: Topically applied FA can greatly exceed MICs for canine pathogenic staphylococci at the most common sites of infection. Topical FA therapy should now be evaluated using available formulations in vivo as an alternative to systemic therapy for canine superficial bacterial folliculitis.Peer reviewedFinal Published versio
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